As we age, estrogen’s role in our bodies can become more apparent. Unfortunately, many health concerns can come with hormone imbalances for men and women. And to help assist with estrogen-to-testosterone imbalances, men often choose to supplement with an estrogen blocker. In this post, we will be discussing what an estrogen blocker is, how they work, review popular products, and answer other FAQs!

What Are They?

The National Cancer Institute (NCI) defines estrogen blockers as a “substance that keeps cells from making or using estrogen.” (1)

Estrogen blockers can have several other terms, such as:

Anti Estrogen Pills
Aromatase Inhibitor
AI

How Do Estrogen Blocker Work?

Testosterone can convert to estradiol through aromatization. Estrogen blockers aim to prevent the conversion of testosterone to estradiol. However, in doing so, other hormone levels can increase. This increase can include gonadotropin-releasing hormone, LH, and follicle-stimulating hormone levels. As a result of these increases, serum testosterone levels also may increase.(2) This can help support an increase in strength, libido, muscle growth, improved mood, and cognition, and fight fatigue. (3,4)

Who Should Take It?

Suppose you have just finished a cycle of pro hormones/a testosterone boosting supplement. In that case, an estrogen blocker could be helpful for a Post Cycle Therapy (PCT) or natural testosterone support. When you increase testosterone, some of this testosterone will convert to estradiol. Therefore, adding a supplement that can impede aromatase synthesis can promote the effects of the testosterone booster more efficiently. (3,4)

High levels of estrogen in men can look like:

Gynecomastia (development of breast tissue)†
Cardiovascular Issues†
Increased Risk of Stroke†
Weight Gain†
Prostate Problems†

estrogen in men infograph

Arimistane VS DIM:

Arimistane or Androsta-3,5-dien-7, 17-dione is a potent anti-estrogen supplement often featured in PCT stacks or taken alone. DIM or 3,3’-Diindolylmethane, on the other hand, is
a plant androgen receptor antagonist. While arimistane is popular for blocking the conversion of testosterone to estradiol, DIM is popular for promoting estrogen metabolism. This effect can support free testosterone without changing total testosterone levels. However, DIM does not raise testosterone and may not block the conversion of testosterone to estradiol. In contrast, AIs like arimistane may increase serum levels of testosterones. (5,6,7)

Arimistane VS DIM

Hi-Tech Pharmaceuticals Arimistane:

Our first estrogen blocker product is Arimistane® by Hi-Tech Pharmaceuticals. It features 50mg per tablet and has the Hi-Tech Pharmaceutical’s signature Cyclosome Delivery™ system. This may improve the delivery and absorption of this product.†

Androsta-3,5-dien-7, 17-dione:

Androsta-3,5-dien-7, 17-dione is a metabolite of 7-Keto DHEA. This ingredient assists with binding to the aromatase enzyme and preventing the conversion of testosterone to estradiol. In return, you may experience an increase in energy, sex drive, and a decrease in fat storage.†

How To Take Hi-Tech Pharmaceuticals Arimistane Estrogen Blocker:

The manufacturer recommends taking one (1) tablet in the morning and one (1) tablet in the evening. Do not exceed two (2) tablets daily.

Customer Review By Lou: “I’ve been using this product on cycle and I have noticed some slight changes in just a few weeks. I like this product because it has a high dosage of Arimistane, and it has done wonders for me. I gained 8lbs in muscle mass and I can’t help but to think this product aided me along the way. Will continue to order!”

Force Factor DIM:

Next, we have Force Factor’s DIM. Similar to Arimistane®, DIM is the main active ingredient in this product. However, DIM generally is taken during PCTs or in a testosterone booster blend. To support the delivery and absorption, Force Factor’s DIM also features Black Pepper Fruit Extract.

DIM:

DIM is a phytochemical found in cruciferous vegetables like broccoli. This ingredient is often in studies for its anti-androgen and anti-cancer properties. But, DIM is unlikely to raise testosterone. On the other hand, though, it may support testosterones effects and estrogen metabolism.(5,8)

BioPerine®:

The other ingredient in this formula is Bioperine®. This ingredient may help increase the bioavailability and absorption of the other ingredients within a formula. (9)

How To Take Force Factor DIM:

The manufacturer recommends taking one (1) capsule daily with a meal.

Customer Review By Andy: “I was on the fence about this product at first. Heard some good reviews and thought I would give it a try. I’m glad I did. I wasn’t expecting to notice changes so fast (first 2 weeks) but some things I noticed was my natural energy levels being higher, sleeping better, and even having fresher looking skin. Overall I think this product could be beneficial to many people.”

Blackstone Labs Eradicate:

Following Force Factor’s DIM, we have our first blend estrogen blocker, Blackstone Lab’s Eradicate. This estrogen blocker features N-Acetyl L-Cysteine, Safed Musli, and Arimistane. Compared to Hi-Tech Pharmaceuticals, Eradicate has half the amount of this ingredient at 25mg per serving. However, the additional ingredients in this formula may also contribute to Eradicate being a potent estrogen blocker and PCT.

N-Acetyl L-Cysteine (NAC):

NAC may assist with prostate support, DHT inhibition, and support healthy liver function.(10)

Safed Musli:

The last ingredient in this formula may be beneficial for it’s properties as a aphrodisiac, adaptogen, and as a potent antioxidant. (11,12)

How To Take Blackstone Lab’s Eradicate:

The manufacturer recommends taking one (1) capsule 1-3 times daily with food. Do not exceed four (4) capsules in a 24 hours. Due to the extreme potency of Eradicate, do not use for longer than eight (8) weeks without a four (4) week off period.

Customer Review By Al: “This product does the job. Haven’t experienced any estrogenic side effects post cycle. I used Eradicate before and feel its better to start taking it prior to the end actual end of your cycle. This way you can avoid issues before they can start.”

REPP Sports Arimivar:

The next product is Repp Sports Arimivar, which features four active ingredients. Of these four ingredients, two are shared with Force Factor’s DIM:

DIM
Black Pepper Extract

In this comparison, Force Factor’s DIM has a higher volume of DIM by 100mg. But like Eradicate, Arimivar has other ingredients that make this a great option for anti-estrogen support.

Chrysin:

Chrysin is a flavonoid that may increase androgen production and inhibit the enzyme aromatase, which converts testosterone into estradiol. (13)

Grape Seed Extract:

Grape Seed Extract may support cardiovascular health and may exhibit aromatase inhibition.(14,15)

How To Take REPP Sport’s Arimivar:

The manufacturer recommends taking 1 serving (2 capsules) of Arimivar with water once daily.

Customer Review By Yammily: “I like that this product delivers on what it is saying it does~ it does take a couple weeks for it to kick in.”

LG Sciences Form XT:

Our final estrogen blocker is Form-XT from LG Sciences, which features three active ingredients, including arimistane. However, Form-XT features the least amount of this ingredient compared to Eradicate and Arimistane®. In addition to this, Form-XT also features resveratrol and epicatechin.

Resveratrol:

Resveratrol compares most closely to Chrysin as these ingredients both may contribute to aromatase inhibition with natural anti-aromatase activity. (16)

Epicatechin:

Similarly, epicatechin may inhibit estradiol and progesterone production. But, more research is necessary to validate these effects. (17)

How To Take LG Science’s Form XT:

The manufacturer recommends taking three (3) tablets per day in divided doses with or without food. Do not exceed 6 tablets per day.

Customer Review By Nicolas: “I’ve been taking this after a cycle of 1-Testosterone, so far so good. Will continue to take!”

Which Should You Try:

When deciding which anti-estrogen product you take where you’re starting from. If you are coming off a prohormone cycle that has risks of estrogen conversion, you may want to choose a higher dosage AI product. Products like Hi-Tech Pharmaceutical’s Arimistane® may be a good option for this. However, if you’re looking for an anti-estrogen product as a way to promote free testosterone levels indirectly, you may benefit from a blend, like Blackstone Lab’s Eradicate or LG Science Form-XT.†

However, if you want to reduce estrogen without altering testosterone levels, Force Factor DIM may be a better option for you. For a better balance between reducing estrogen and naturally boosting testosterone, Arimivar from Repp Sports may be the best option for you.

Anti-Estrogen FAQs:

In this section, we’ll be diving into some of your most frequently asked questions about estrogen blockers!

Are Estrogen Blockers Legal?
Yes! Estrogen blockers like the ones we mentioned in this post are readily available. However, these products may be banned by some sports organizations and/or increase the risk of false positives on a drug test. If this concerns you, we recommend contacting your sports organization or physician before taking any estrogen blocker. †
Are Anti-Estrogen Supplements Safe For Women?
Hormone therapy is a common treatment option for many women’s health issues. However, the abovementioned products do not specifically state they are safe for women. Therefore, we would advise women interested in taking an estrogen blocker to consult a physician first.†
Can Estrogen Blockers Help Weight Loss?
Taking an estrogen blocker may assist in weight loss if excess estrogen is causing your weight gain, fat retention, or water weight/bloating. However, these products are not directly for weight loss, so we wouldn’t recommend that users take an estrogen blocker solely.†
Can Estrogen Blockers Cause Joint Pain?
There is evidence that estrogen blockers may be associated with joint pain or stiffness. However, regular exercise and weight loss may assist with joint pain and stiffness relief. (18)
What Is The Difference Between Estrogen Blocker VS Testosterone Boosters?
While many testosterone boosters feature an estrogen blocker, estrogen blockers themselves are not usually the best option for direct testosterone boosting properties.† Luckily, many options are available for natural testosterone boosters with estrogen blockers like Arimiplex by Hi-Tech Pharmaceuticals.

Wrapping Up:

And this marks the end of our post on estrogen blockers. Thank you for reading! And as always, if there was something that wasn’t clear, another question you might have, or if you have another idea for a blog, Email Us!

Are you looking for more to read? Check out some of our other blogs!

Warnings And Side Effects:

First it is important to note these products are only intended for the consumption of healthy adults 18 years of age or older. However, these products may not be suitable for individuals under 21. Additionally, pregnant or nursing (breastfeeding) women should not use this product.

Do not use these products if you are at risk for or are in treatment for prostate disease, heart disease, or other medical conditions.

Stop use immediately if you experience:

Rapid heart beat
Dizziness
Vomiting
Other similar symptoms

These products may contain ingredients that are banned by some sports organizations and/or increase risk of false positive on a drug test. Please consult with your sport organization or physician before taking this product.

Allergen Warning:

The products mentioned above may be manufactured in a plant that also processes:

Milk
Egg
Soy
Peanut
Fish
Crustaceans/shellfish
Tree nuts
Wheat products

Disclaimer:

†Please note the intention of the information provided is for reference only. Furthermore, we are in no way providing medical advice or instruction. Instead, the information provided in this guide/blog utilizes anecdotal information and available studies/reviews. While our goal is to maintain and display accurate information, we can’t guarantee it represents the latest formulation of the product or information. Therefore, please visit the manufacturer’s website if you have any concerns. Also, the information above does not represent our views here at Same Day Supplements. Instead, these are the manufacturers’ and users’ views and information. Additionally, the Food and Drug Administration has not evaluated these statements. Finally, the intention of these products is not to diagnose, treat, cure or prevent any disease or illness.

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Best Anti Estrogen Supplements For Men Review